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If ingestion butamirata rapidly and completely absorbed. Relationship to plasma proteins is 94%. It is metabolized to form two metabolites also possess antitussive effect. Metabolites are mainly (90%) by the kidneys, and only a small portion of the bowel.

Gvayfenezin ingestion is rapidly test sustanon absorbed from the gastrointestinal tract. Relationship to plasma proteins is insignificant. It gvayfenezin rapidly metabolized to inactive metabolites that are excreted by the kidneys. T 1/2 – 1 hour.

Indications
Dry and irritating cough of various etiologies (including the infektsionnovospalitelnyh diseases of the upper and lower respiratory tract).

Contraindications
: Hypersensitivity to the components of the drug components; myasthenia gravis; Children up to age 12 years; I trimester of pregnancy; during breastfeeding.

Pregnancy and lactation
The drug Stoptussin should not be test sustanon used in I trimester of pregnancy. If necessary, its use in the II and III trimester of pregnancy, make sure that the intended benefits to the mother outweighs the potential risk to the fetus. There is no reliable information about the penetration butamirata and guaifenesin passes into breast milk. You must stop breast-feeding for a period of application of the drug Stoptussin.

Dosing and Administration
Inside, the food, without chewing, with some liquid (water, tea, fruit juice, etc.). The dose depends on the body weight of the patient. Adults and children over 12 years of age with a weightless than 50 kg:1/2 tablet 4 times a day – from 50 to 70 kg: 1 tablet 3 times a day – from 70 to 90 kg: 12 tablet 3 times a day – more than 90 kg: 1/2 tablet 4 times a day.

 

The interval between doses should be 4-6 hours.

Side effects
Under the recommended dosing regimen, patients usually tolerate the drug well. There may be nausea, vomiting, diarrhea, loss of appetite, stomach pain, dizziness, headache, drowsiness, skin rash, and urticaria. These effects occur in approximately 1% of patients and usually disappear without a dose reduction.

The frequency of adverse reactions listed below was determined according to the following criteria: very often (at least 1.10), frequent (more than 1/100, less than 1.10); rare (more than 1/1000, less than 1/100); rarely (over 1/10000, 1/1000 less); very rare (less than 1/10000), including isolated reports.

On the part of the central nervous system: often – headache.

On the part of the organ of hearing and balance: often -golovokruzhenie.

On the part of the digestive system: often -toshnota, anorexia, abdominal pain, vomiting, diarrhea; very rarely – a bitter taste in the mouth, heartburn, feeling of heaviness in the epigastrium.

From the respiratory system: rarely -odyshka.

Since the cardiovascular system: rarely – pain in the chest; very rarely – tachycardia, palpitations.

Skin and subcutaneous tissue: very rarely – itching, rash, hives, “hot flashes.”

Other: very rarely – pain around the eyes.

Overdose Symptoms predominate signs of toxic effects of guaifenesin: sleepiness, muscle weakness, nausea and vomiting, urolithiasis. Treatment: consult your doctor. Gvayfenezin has no specific antidote. Assign a gastric lavage, reception activated carbon, symptomatic therapy (support the cardiovascular, respiratory and renal function, electrolyte balance).

Interaction with other drugs
Gvayfenezin enhances the analgesic test sustanon effect of paracetamol and acetylsalicylic acid; enhances the effect of alcohol, sedatives, hypnotics and general anesthetics on the central nervous system; It enhances the action of muscle relaxants.
Concentrations vanillylmandelic and 5-hydroxyindoleacetic acid using nitrozonaftola in false positive results can be obtained as a reactant. Therefore guaifenesin treatment should be discontinued 48 hours prior to urine collection for this analysis.

Cautions
If symptoms persist, consider modifying treatment. The drug should not be administered with productive cough patients suffering from prolonged or chronic coughing (including those caused by smoking), bronchitis or emphysema.

Effects on ability to drive and work with the technique:
drug Stoptussin may adversely affect the ability to drive and to classes in other potentially hazardous activities that require high concentration and psychomotor speed reactions, due to the fact that it can cause dizziness and other side effects. soma max 10 testosterone reviews bodybuilding pain o soma healthy food for bodybuilding

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