Allergic reactions sustanon 250: urticaria, chills or fever, rash, pruritus, rarely – bronchospasm, eosinophilia, Stevens-Johnson syndrome, erythema polymorphous exudative, serum sickness, angioedema, anaphylactic shock. With storota digestive system: nausea, vomiting, diarrhea, or constipation, flatulence, abdominal pain, taste disturbance, stomatitis, glossitis, pseudomembranous enterocolitis, liver dysfunction (increased activity of “liver” transaminases, less often – ALP or bilirubin, cholestatic jaundice), dysbiosis. From the side of hematopoiesis: leukopenia, neutropenia, granulocytopenia , lymphopenia, thrombocytosis, thrombocytopenia, hemolytic anemia, anticoagulation, lowering of plasma coagulation factors , prolonged prothrombin time. From the urinary system: renal dysfunction (azotemia, increased urea in the blood, hypercreatininemia , glucosuria, cylindruria, hematuria), oliguria, anuria. Local reactions: phlebitis, pain along the vein, pain and infiltration in the ground / m introduction. Other: headache, dizziness, nosebleeds, candidiasis, superinfection.
Ceftriaxone and aminoglycosides have synergistic against many gram-negative bacteria.
Incompatible with ethanol.
NSAIDs, and others. Platelet aggregation inhibitors increase the chance of bleeding.
In an application with the “loop” diuretics, etc. The risk of increased nephrotoxic drugs nephrotic effect.
Pharmaceutical incompatible sustanon 250 with solutions containing other. antibiotics.
You can not mix in the same infusion vial or a syringe with other antibiotic (chemical incompatibility).
Excessively high concentrations of ceftriaxone in plasma can not be reduced by hemodialysis or peritoneal dialysis. For treatment of overdose symptomatic measures are recommended.
Ceftriaxone is used only in a hospital.
When simultaneous severe renal and hepatic impairment should be regular monitoring of the concentration of drug in plasma.
In patients on hemodialysis, you must monitor the concentration of ceftriaxone in plasma, because have its elimination rate may be reduced.
In the long-term treatment should regularly monitor the picture of peripheral blood indicators of the functional state of the liver and kidneys.
On rare occasions, ultrasound gallbladder sustanon 250 marked darkening, which disappear after the cancellation (even if this phenomenon is accompanied by pain in the right hypochondria, recommends continuation of the appointment of an antibiotic and conduct symptomatic treatment).
During treatment contraindicated use of ethanol – can disulfiramipodobnye effects (facial flushing, abdominal cramps and in the stomach, nausea, vomiting, headache, decreased blood pressure, tachycardia, shortness of breath).
in spite of the detailed medical history, that is the rule for other cephalosporin antibiotics, can not exclude the possibility of an anaphylactic shock, which require immediate treatment – first intravenous adrenaline, then glucocorticoids.
Studies in vitro have shown that, like other cephalosporin antibiotics ceftriaxone is able to displace bilirubin bound to albumin serum. Therefore, in infants with hyperbilirubinemia and especially in premature infants, the use of ceftriaxone requires even more care.
With long-term use requires periodic monitoring of blood formula. Freshly prepared solutions of ceftriaxone is physically and chemically stable for 6 hours at room temperature.
In the appointment during lactation should be abolished breastfeeding.
Elderly or debilitated patients may require vitamin C.